ATG9B-H154A
Family ：
Apoptosis
Catalog No. ：
ATG9B-H154A
Protein ：
ATG9B
UniProt ：
Q674R7
Organism ：
Homo sapiens
Expression system ：
Mammalian cell
Tag ：
His/MBP/Flag
Sequence ：
M1-D924
Assay ：
Structure ：
Inquiry ：
是
Product Information
Symbol/Gene Name: ATG9B
Alias: Autophagy-related protein 9B,APG9-like 2,Nitric oxide synthase 3-overlapping antisense gene protein,Protein sONE
Uniprot: Q674R7
Background: Phospholipid scramblase involved in autophagy by mediating autophagosomal membrane expansion. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 (ATG2A or ATG2B) from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion (By similarity). In addition to autophagy, also plays a role in necrotic cell death (By similarity).
Construct: 8His-MBP-TEV-(G)-ATG9B(M1-D924 end)-Flag
Expression Host: Mammalian cells
Purity: 90%
Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
Supplied as sterile
Please contact us for any concerns or special requirements.
Please refer to the specific buffer information in the hard copy of CoA.
Endotoxin:
< 0.01 EU per μg of the protein
Shipping:
Liquid. It is shipped out with blue ice.
Stability & Storage:
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Recombinant protein