Catalog No. ：
Expression system ：
eGFP, Strep II,10His
Symbol/Gene Name: ABCC1
Alias: Multidrug resistance-associated protein 1,ATP-binding cassette sub-family C member 1,Glutathione-S-conjugate-translocating ATPase ABCC1,Leukotriene C(4) transporter,LTC4 transporter
Background: Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs by decreasing accumulation of drug in cells, and by mediating ATP- and GSH-dependent drug export (PubMed:12067707). Hydrolyzes ATP with low efficiency. Catalyzes the export of sphingosine 1-phosphate from mast cells independently of their degranulation (By similarity). Participates in inflammatory response by allowing export of leukotriene C4 from leukotriene C4-synthezing cells (By similarity).
Construct: bABCC1(M1-V1530 end) (E1454Q)-3C-eGFP-Strep II-10His
Expression Host: Mammalian
Formulation: 50 mM Tris-HCl (pH 8.0), 150mM KCl, 2mM DTT, 2mM MgCl2, 5% glycerol, 0.06% digitonin
Please contact us for any concerns or special requirements.
Please refer to the specific buffer information in the hard copy of CoA.
< 0.01 EU per μg of the protein
Liquid. It is shipped out with blue ice.
Stability & Storage:
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.