BACH2-H00A
Family :
E3 ubiquitin-protein ligase
Catalog No. :
BACH2-H00A
Protein :
BACH2
UniProt :
Q9BYV9
Organism :
Homo sapiens
Expression system :
Insect cell
Tag :
No tag
Sequence :
S2-T841
Assay :
Structure :
Inquiry :
是
Product Information
Symbol/Gene Name: BACH2
Alias: Transcription regulator protein BACH2,BTB and CNC homolog 2
Uniprot: Q9BYV9
Background: Transcriptional regulator that acts as repressor or activator (By similarity). Binds to Maf recognition elements (MARE) (By similarity). Plays an important role in coordinating transcription activation and repression by MAFK (By similarity). Induces apoptosis in response to oxidative stress through repression of the antiapoptotic factor HMOX1 (PubMed:17018862). Positively regulates the nuclear import of actin (By similarity). Is a key regulator of adaptive immunity, crucial for the maintenance of regulatory T-cell function and B-cell maturation (PubMed:28530713).
Construct: (GG)-BACH2(S2-T841 end)
Expression Host: Insect cell
Purity: 90%
Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
Supplied as sterile
Please contact us for any concerns or special requirements.
Please refer to the specific buffer information in the hard copy of CoA.
Endotoxin:
< 0.01 EU per μg of the protein
Shipping:
Liquid. It is shipped out with blue ice.
Stability & Storage:
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Recombinant protein