TRIP13-H00A
Family ：
Protease and Enzyme
Catalog No. ：
TRIP13-H00A
Protein ：
TRIP13
UniProt ：
Q15645
Organism ：
Homo sapiens
Expression system ：
E. coli
Tag ：
No tag
Sequence ：
M1-I432
Assay ：
Structure ：
Inquiry ：
是
Symbol/Gene Name: TRIP13
Alias: Pachytene checkpoint protein 2 homolog,Human papillomavirus type 16 E1 protein-binding protein,16E1-BP,HPV16 E1 protein-binding protein,Thyroid hormone receptor interactor 13,Thyroid receptor-interacting protein 13,TR-interacting protein 13,TRIP-13
Uniprot: Q15645
Background: Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation. In males, required for efficient synapsis of the sex chromosomes and for sex body formation. Promotes early steps of the DNA double-strand breaks (DSBs) repair process upstream of the assembly of RAD51 complexes. Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes (By similarity). Plays a role in mitotic spindle assembly checkpoint (SAC) activation (PubMed:28553959).
Construct: GG-TRIP13(M1-I432 end)
Expression Host: E. coli
Purity: 90%
Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
Supplied as sterile
Please contact us for any concerns or special requirements.
Please refer to the specific buffer information in the hard copy of CoA.
Endotoxin:
< 0.01 EU per μg of the protein
Shipping:
Liquid. It is shipped out with blue ice.
Stability & Storage:
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Recombinant protein