BP11517-00A

Family :

Kinase

Catalog No. :

BP11517-00A

Protein :

PKMYT1

UniProt :

Q99640

Organism :

Homo sapiens

Expression system :

Insect cell

Tag :

No tag

Sequence :

L2-T499

Inquiry :

Symbol/Gene Name:  PKMYT1

Alias:  Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase,Myt1 kinase

Uniprot: Q99640

Background: Acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase specifically when CDK1 is complexed to cyclins. Mediates phosphorylation of CDK1 predominantly on 'Thr-14'. Also involved in Golgi fragmentation. May be involved in phosphorylation of CDK1 on 'Tyr-15' to a lesser degree, however tyrosine kinase activity is unclear and may be indirect. May be a downstream target of Notch signaling pathway during eye development.

Construct: GG-PKMYT1(L2-T499 end)

Expression Host: Insect cell

Purity: 90%

Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol

Supplied as sterile

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.