PKMYT1-H12A
Family ：
Kinase
Catalog No. ：
PKMYT1-H12A
Protein ：
PKMYT1
UniProt ：
Q99640
Organism ：
Homo sapiens
Expression system ：
Insect cell
Tag ：
His/GST
Sequence ：
L2-T499
Assay ：
Structure ：
Inquiry ：
是
Symbol/Gene Name: PKMYT1
Alias: Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase,Myt1 kinase
Uniprot: Q99640
Background: Acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase specifically when CDK1 is complexed to cyclins. Mediates phosphorylation of CDK1 predominantly on 'Thr-14'. Also involved in Golgi fragmentation. May be involved in phosphorylation of CDK1 on 'Tyr-15' to a lesser degree, however tyrosine kinase activity is unclear and may be indirect. May be a downstream target of Notch signaling pathway during eye development.
Construct: 8His-GST-TEV-GG-PKMYT1(L2-T499 end)
Expression Host: Insect cell
Purity: 90%
Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
Supplied as sterile
Please contact us for any concerns or special requirements.
Please refer to the specific buffer information in the hard copy of CoA.
Endotoxin:
< 0.01 EU per μg of the protein
Shipping:
Liquid. It is shipped out with blue ice.
Stability & Storage:
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Recombinant protein