reductase-H00A
Family ：
Protease and Enzyme
Catalog No. ：
reductase-H00A
Protein ：
Aldose-reductase
UniProt ：
O60218
Organism ：
Homo sapiens
Expression system ：
E. coli
Tag ：
No tag
Sequence ：
M1-Y316
Assay ：
Structure ：
Inquiry ：
是
Symbol/Gene Name: AKR1B10
Alias: Aldo-keto reductase family 1 member B10,ARL-1,Aldose reductase-like,Aldose reductase-related protein,ARP,hARP,Small intestine reductase,SI reductase
Uniprot: O60218
Background: Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols (PubMed:9565553, PubMed:18087047, PubMed:12732097, PubMed:19013440, PubMed:19563777). Displays strong enzymatic activity toward all-trans-retinal, 9-cis-retinal, and 13-cis-retinal (PubMed:12732097, PubMed:18087047). Plays a critical role in detoxifying dietary and lipid-derived unsaturated carbonyls, such as crotonaldehyde, 4-hydroxynonenal, trans-2-hexenal, trans-2,4-hexadienal and their glutathione-conjugates carbonyls (GS-carbonyls) (PubMed:19013440, PubMed:19563777). Displays no reductase activity towards glucose (PubMed:12732097).
Construct: Aldose-reductase(M1-Y316 end)
Expression Host: E. coli
Purity: 90%
Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
Supplied as sterile
Please contact us for any concerns or special requirements.
Please refer to the specific buffer information in the hard copy of CoA.
Endotoxin:
< 0.01 EU per μg of the protein
Shipping:
Liquid. It is shipped out with blue ice.
Stability & Storage:
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Recombinant protein