CSNK1A1-H00A

Family :

Kinase

Catalog No. :

CSNK1A1-H00A

Protein :

CSNK1A1

UniProt :

P48729

Organism :

Homo sapiens

Expression system :

Insect cell

Tag :

No tag

Sequence :

A2-F337

Assay :

Structure :

Inquiry :

Product Information

Symbol/Gene Name:  CSNK1A1

Alias:  Casein kinase I isoform alpha,CKI-alpha,CK1

Uniprot: P48729

Background: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis (PubMed:11955436, PubMed:1409656, PubMed:18305108). May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration (PubMed:23902688).

Construct: GG-CSNK1A1 (CK1a) (A2-F337 end)

Expression Host: Insect cell

Purity: 90%

Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.