SENP7-H02C
Family ：
DUBs
Catalog No. ：
SENP7-H02C
Protein ：
SENP7
UniProt ：
Q9BQF6
Organism ：
Homo sapiens
Expression system ：
E. coli
Tag ：
GST
Sequence ：
T640-P984
Assay ：
Structure ：
Inquiry ：
是
Symbol/Gene Name: SENP7
Alias: Sentrin-specific protease 7,SUMO-1-specific protease 2,Sentrin/SUMO-specific protease SENP7
Uniprot: Q9BQF6
Background: Protease that acts as a positive regulator of the cGAS-STING pathway by catalyzing desumoylation of CGAS. Desumoylation of CGAS promotes DNA-binding activity of CGAS, subsequent oligomerization and activation (By similarity). Deconjugates SUMO2 and SUMO3 from targeted proteins, but not SUMO1 (PubMed:18799455). Catalyzes the deconjugation of poly-SUMO2 and poly-SUMO3 chains (PubMed:18799455). Has very low efficiency in processing full-length SUMO proteins to their mature forms (PubMed:18799455).
Construct: GST-TEV-GG-SENP7(T640-P984)
Expression Host: E. coli
Purity: 90%
Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
Supplied as sterile
Please contact us for any concerns or special requirements.
Please refer to the specific buffer information in the hard copy of CoA.
Endotoxin:
< 0.01 EU per μg of the protein
Shipping:
Liquid. It is shipped out with blue ice.
Stability & Storage:
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Recombinant protein