FIP1L1-H12A
Family ：
Kinase
Catalog No. ：
FIP1L1-H12A
Protein ：
FIP1L1
UniProt ：
Q6UN15
Organism ：
Homo sapiens
Expression system ：
Insect cell
Tag ：
His/GST
Sequence ：
S2-E594
Assay ：
Structure ：
Inquiry ：
是
Product Information
Symbol/Gene Name: FIP1L1
Alias: Pre-mRNA 3'-end-processing factor FIP1,hFip1,FIP1-like 1 protein,Factor interacting with PAP,Rearranged in hypereosinophilia
Uniprot: Q6UN15
Background: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. FIP1L1 contributes to poly(A) site recognition and stimulates poly(A) addition. Binds to U-rich RNA sequence elements surrounding the poly(A) site. May act to tether poly(A) polymerase to the CPSF complex.
Construct: 8His-GST-TEV-GG-FIP1L1(S2-E594 end)
Expression Host: Insect cell
Purity: 90%
Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
Supplied as sterile
Please contact us for any concerns or special requirements.
Please refer to the specific buffer information in the hard copy of CoA.
Endotoxin:
< 0.01 EU per μg of the protein
Shipping:
Liquid. It is shipped out with blue ice.
Stability & Storage:
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Recombinant protein