BP14622-00A

Family :

Protease and Enzyme

Catalog No. :

BP14622-00A

Protein :

FNTA

UniProt :

P49354

Organism :

Homo sapiens

Expression system :

E. coli

Tag :

No tag

Sequence :

M1-Q379

Inquiry :

Product Information

Symbol/Gene Name:  FNTA

Alias:  Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha,CAAX farnesyltransferase subunit alpha,FTase-alpha,Ras proteins prenyltransferase subunit alpha,Type I protein geranyl-geranyltransferase subunit alpha,GGTase-I-alpha

Uniprot: P49354

Background: Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation.

Construct: GG-FNTA(M1-Q379 end)

Expression Host: E. coli

Purity: 90%

Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol

Supplied as sterile

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.