FRK-H02A

Family :

Kinase

Catalog No. :

FRK-H02A

Protein :

FRK

UniProt :

P42685

Organism :

Homo sapiens

Expression system :

Insect cell

Tag :

GST

Sequence :

S2-R505

Assay :

Structure :

Inquiry :

Product Information

Symbol/Gene Name:  FRK

Alias:  Tyrosine-protein kinase FRK,FYN-related kinase,Nuclear tyrosine protein kinase RAK,Protein-tyrosine kinase 5

Uniprot: P42685

Background: Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation. Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4. May function as a tumor suppressor.

Construct: GST-TEV-GG-FRK(S2-R505 end)

Expression Host: Insect cell

Purity: 90%

Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol

Supplied as sterile

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.