GLP1R-H41AI

Family :

GPCR

Catalog No. :

GLP1R-H41AI

Protein :

GLP1R

UniProt :

P43220

Organism :

Homo sapiens

Expression system :

Insect cell

Tag :

Flag,10His

Sequence :

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Assay :

Structure :

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Product Information

Symbol/Gene Name:  GLP1R

Alias:  Glucagon-like peptide 1 receptor,GLP-1 receptor,GLP-1-R,GLP-1R

Uniprot: P43220

Background: G-protein coupled receptor for glucagon-like peptide 1 (GLP-1) (PubMed:8405712, PubMed:8216285, PubMed:7517895, PubMed:19861722, PubMed:26308095, PubMed:27196125, PubMed:28514449). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels (PubMed:8405712, PubMed:8216285, PubMed:7517895, PubMed:19861722, PubMed:26308095, PubMed:27196125, PubMed:28514449). Plays a role in regulating insulin secretion in response to GLP-1 (By similarity).

Construct: Flag-10His-TEV-GLP1R(R24-F257) (S193C, I196F, S225A, M233C)-VRLLSGSREKDRNLR-GLP1R(Q263-K437) (S271A, I317C, G318I, K346A, C347F, G361C)

Expression Host: Insect cell

Purity: 70%

Formulation: 20 mM HEPES pH 7.5, 100 mM NaCl, 0.00075% (w/v) LMNG, 0.00015% (w/v) CHS and 0.00025% (w/v) GDN, 100 uM TCEP

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.