Glucokinase-H01A
Family ：
Kinase
Catalog No. ：
Glucokinase-H01A
Protein ：
Glucokinase
UniProt ：
Q14397
Organism ：
Homo sapiens
Expression system ：
Insect cell
Tag ：
His
Sequence ：
M1-Q625
Assay ：
Structure ：
Inquiry ：
是
Product Information
Symbol/Gene Name: GCKR
Alias: Glucokinase regulatory protein,GKRP,Glucokinase regulator
Uniprot: Q14397
Background: Regulates glucokinase (GCK) by forming an inactive complex with this enzyme (PubMed:23621087, PubMed:23733961). Acts by promoting GCK recruitment to the nucleus, possibly to provide a reserve of GCK that can be quickly released in the cytoplasm after a meal (PubMed:10456334). The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6-phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity (PubMed:23621087, PubMed:23733961).
Construct: 8His-TEV-Glucokinase(M1-Q625 end)
Expression Host: Insect cell
Purity: 90%
Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
Supplied as sterile
Please contact us for any concerns or special requirements.
Please refer to the specific buffer information in the hard copy of CoA.
Endotoxin:
< 0.01 EU per μg of the protein
Shipping:
Liquid. It is shipped out with blue ice.
Stability & Storage:
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Recombinant protein