BP10188-00A

Family :

Kinase

Catalog No. :

BP10188-00A

Protein :

LOK

UniProt :

O94804

Organism :

Homo sapiens

Expression system :

Insect cell

Tag :

No tag

Sequence :

M1-S348

Inquiry :

Symbol/Gene Name:  STK10

Alias:  Serine/threonine-protein kinase 10,Lymphocyte-oriented kinase

Uniprot: O94804

Background: Serine/threonine-protein kinase involved in regulation of lymphocyte migration. Phosphorylates MSN, and possibly PLK1. Involved in regulation of lymphocyte migration by mediating phosphorylation of ERM proteins such as MSN. Acts as a negative regulator of MAP3K1/MEKK1. May also act as a cell cycle regulator by acting as a polo kinase kinase: mediates phosphorylation of PLK1 in vitro; however such data require additional evidences in vivo.

Construct: LOK(M1-S348)

Expression Host: Insect cell

Purity: 90%

Formulation: 50mM Tris-HCl (pH 7.5), 200mM NaCl, 20% glycerol

Supplied as sterile

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.