BP14260-01A

Family :

membrane protein

Catalog No. :

BP14260-01A

Protein :

JAGN1

UniProt :

Q8N5M9

Organism :

Homo sapiens

Expression system :

Mammalian cell

Tag :

10His

Sequence :

M1-K183

Inquiry :

Symbol/Gene Name:  JAGN1

Alias:  Protein jagunal homolog 1

Uniprot: Q8N5M9

Background: Endoplasmic reticulum transmembrane protein involved in vesicle-mediated transport, which is required for neutrophil function. Required for vesicle-mediated transport; it is however unclear whether it is involved in early secretory pathway or intracellular protein transport. Acts as a regulator of neutrophil function, probably via its role in vesicle-mediated transport: required for defense against fungal pathogens and for granulocyte colony-stimulating factor (GM-CSF) signaling pathway; possibly by regulating glycosylation and/or targeting of proteins contributing to the viability and migration of neutrophils.

Construct: sfGFP(M1-N144)-JAGN1(M1-K183 end)-sfGFP(N146-T230)-10His

Expression Host: Mammalian

Purity: 70%

Formulation: 20 mM Tris-HCl (pH 8.0), 150 mM NaCl, 0.02% LMNG

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.