BP11169-12A

Family :

Kinase

Catalog No. :

BP11169-12A

Protein :

MAPK4

UniProt :

P31152

Organism :

Homo sapiens

Expression system :

Insect cell

Tag :

His/GST

Sequence :

A2-W587

Inquiry :

Symbol/Gene Name:  MAPK4

Alias:  Mitogen-activated protein kinase 4,MAP kinase 4,MAPK 4,Extracellular signal-regulated kinase 4,ERK-4,MAP kinase isoform p63,p63-MAPK

Uniprot: P31152

Background: Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated at Ser-186 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK4/MAPK4. May promote entry in the cell cycle (By similarity).

Construct: 8His-GST-TEV-GG-MAPK4(A2-W587 end)

Expression Host: Insect cell

Purity: 90%

Formulation: 50mM Tris-HCl (pH 7.5), 200mM NaCl, 20% glycerol

Supplied as sterile

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.