SLC22A2-H154B
Family ：
SLC
Catalog No. ：
SLC22A2-H154B
Protein ：
SLC22A2
UniProt ：
O15244
Organism ：
Homo sapiens
Expression system ：
Insect cell
Tag ：
8His-MBP,Flag
Sequence ：
P2-N555
Assay ：
Structure ：
Inquiry ：
是
Symbol/Gene Name: SLC22A2
Alias: Solute carrier family 22 member 2,Organic cation transporter 2,hOCT2
Uniprot: O15244
Background: Mediates tubular uptake of organic compounds from circulation. Mediates the influx of agmatine, dopamine, noradrenaline (norepinephrine), serotonin, choline, famotidine, ranitidine, histamine, creatinine, amantadine, memantine, acriflavine, 4-[4-(dimethylamino)-styryl]-N-methylpyridinium ASP, amiloride, metformin, N-1-methylnicotinamide (NMN), tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, cisplatin and oxaliplatin. Cisplatin may develop a nephrotoxic action. Transport of creatinine is inhibited by fluoroquinolones such as DX-619 and LVFX. This transporter is a major determinant of the anticancer activity of oxaliplatin and may contribute to antitumor specificity.
Construct: 8His-MBP-TEV-(GG)-SLC22A2(P2-N555)-Flag
Expression Host: Insect cell
Purity: 80%
Formulation:
Please contact us for any concerns or special requirements.
Please refer to the specific buffer information in the hard copy of CoA.
Endotoxin:
< 0.01 EU per μg of the protein
Shipping:
Liquid. It is shipped out with blue ice.
Stability & Storage:
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Recombinant protein