NTCP-H31D
Family ：
NTC
Catalog No. ：
NTCP-H31D
Protein ：
NTCP
UniProt ：
Q14973
Organism ：
Homo sapiens
Expression system ：
Mammalian cell
Tag ：
eGFP,Strep II,10His
Sequence ：
M1-A349
Assay ：
Structure ：
Inquiry ：
是
Symbol/Gene Name: SLC10A1
Alias: Sodium/bile acid cotransporter,Cell growth-inhibiting gene 29 protein,Na(+)/bile acid cotransporter,Na(+)/taurocholate transport protein,Sodium/taurocholate cotransporting polypeptide,Solute carrier family 10 member 1
Uniprot: Q14973
Background: As a major transporter of conjugated bile salts from plasma into the hepatocyte, it has a key role in the enterohepatic circulation of bile salts necessary for the solubilization and absorption of dietary fat and fat-soluble vitamins. It exhibits broad substrate specificity and transports various non-bile acid organic compounds as well. It is strictly dependent on the extracellular presence of sodium. Able to transport taurocholate, cholate, and the non-bile acid estron sulfate (PubMed:14660639, PubMed:24867799).
Construct: NTCP(M1-A349 end)-3C-eGFP-Strep II-10His
Expression Host: Mammalian
Purity: 90%
Formulation:
Supplied as sterile 50 mM HEPES pH 7.5, 150 mM NaCl, 0.005% (w/v) LMNG
Please contact us for any concerns or special requirements.
Please refer to the specific buffer information in the hard copy of CoA.
Endotoxin:
< 0.01 EU per μg of the protein
Shipping:
Liquid. It is shipped out with blue ice.
Stability & Storage:
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Recombinant protein