SLC25A11-H154C

Family :

SLC

Catalog No. :

SLC25A11-H154C

Protein :

SLC25A11

UniProt :

Q02978

Organism :

Homo sapiens

Expression system :

Insect cell

Tag :

8His-MBP,Flag

Sequence :

A2-G314

Assay :

Structure :

Inquiry :

Symbol/Gene Name:  SLC25A11

Alias:  Mitochondrial 2-oxoglutarate/malate carrier protein,OGCP,Solute carrier family 25 member 11

Uniprot: Q02978

Background: Catalyzes the transport of 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for malate or other dicarboxylic acids, and plays an important role in several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, in gluconeogenesis from lactate, and in nitrogen metabolism. Maintains mitochondrial fusion and fission events, and the organization and morphology of cristae (PubMed:21448454). Involved in the regulation of apoptosis (By similarity). Acts as a tumor-suppressor gene implicated in the predisposition to metastatic paraganglioma.

Construct: 8His-MBP-TEV-(GG)-SLC25A11(A2-G314)-Flag

Expression Host: Insect cell

Purity: 80%

Formulation:

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.