OX2R-H41D

Family :

GPCR

Catalog No. :

OX2R-H41D

Protein :

OX2R

UniProt :

O43614

Organism :

Homo sapiens

Expression system :

Insect cell

Tag :

Flag/10His

Sequence :

K294-H388

Assay :

Structure :

Inquiry :

Symbol/Gene Name:  HCRTR2

Alias:  Orexin receptor type 2,Ox-2-R,Ox2-R,Ox2R,Hypocretin receptor type 2

Uniprot: O43614

Background: Nonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides (PubMed:9491897, PubMed:26950369). Triggers an increase in cytoplasmic Ca(2+) levels in response to orexin-A binding (PubMed:9491897, PubMed:26950369).

Construct: HA(signal peptide)-Flag-OX2R(M1-Q254)-PGS protein-OX2R(K294-H388)-10His

Expression Host: Insect cell

Purity: 90%

Formulation:

Supplied as sterile 20 mM HEPES (pH 7.5), 150 mM NaCl, 1 μM suvorexant, 0.05% LMNG, 0.005% CHS, 0.005% sodium cholate

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.

Endotoxin:

< 0.01 EU per μg of the protein

Shipping:

Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.