SLC40A1-H154B
Family ：
SLC
Catalog No. ：
SLC40A1-H154B
Protein ：
SLC40A1
UniProt ：
Q9NP59
Organism ：
Homo sapiens
Expression system ：
Insect cell
Tag ：
8His-MBP,Flag
Sequence ：
T2-V571
Assay ：
Structure ：
Inquiry ：
是
Symbol/Gene Name: SLC40A1
Alias: Solute carrier family 40 member 1,Ferroportin-1,Iron-regulated transporter 1
Uniprot: Q9NP59
Background: Major iron transporter that plays a key role in balancing cellular and systemic iron levels (PubMed:29237594, PubMed:22682227, PubMed:15692071). Transports iron from intestinal, splenic, and hepatic cells into the blood to provide iron to other tissues (By similarity). Controls therefore dietary iron uptake, iron recycling by macrophages, and release of iron stores in hepatocytes (By similarity). When iron is in excess, hepcidin/HAMP levels increase resulting in a degradation of ferroportin/SLC40A1 limiting the iron efflux to plasma (PubMed:22682227, PubMed:29237594, PubMed:32814342).
Construct: 8His-MBP-TEV-(GG)-SLC40A1(T2-V571 end)-Flag
Expression Host: Insect cell
Purity: 90%
Formulation:
Please contact us for any concerns or special requirements.
Please refer to the specific buffer information in the hard copy of CoA.
Endotoxin:
< 0.01 EU per μg of the protein
Shipping:
Liquid. It is shipped out with blue ice.
Stability & Storage:
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Recombinant protein