PAK6-H01A
Family ：
Kinase
Catalog No. ：
PAK6-H01A
Protein ：
PAK6
UniProt ：
Q9NQU5
Organism ：
Homo sapiens
Expression system ：
E. coli
Tag ：
His
Sequence ：
G383-Y674
Assay ：
Structure ：
Inquiry ：
是
Symbol/Gene Name: PAK6
Alias: Serine/threonine-protein kinase PAK 6,PAK-5,p21-activated kinase 6,PAK-6
Uniprot: Q9NQU5
Background: Serine/threonine protein kinase that plays a role in the regulation of gene transcription. The kinase activity is induced by various effectors including AR or MAP2K6/MAPKK6. Phosphorylates the DNA-binding domain of androgen receptor/AR and thereby inhibits AR-mediated transcription. Inhibits also ESR1-mediated transcription. May play a role in cytoskeleton regulation by interacting with IQGAP1. May protect cells from apoptosis through phosphorylation of BAD.
Construct: 6His-TEV-PAK6(G383-Y674)
Expression Host: E. coli
Purity: 90%
Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
Supplied as sterile
Please contact us for any concerns or special requirements.
Please refer to the specific buffer information in the hard copy of CoA.
Endotoxin:
< 0.01 EU per μg of the protein
Shipping:
Liquid. It is shipped out with blue ice.
Stability & Storage:
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Recombinant protein