HLTF-H00A
Family ：
E3 ubiquitin-protein ligase
Catalog No. ：
HLTF-H00A
Protein ：
HLTF
UniProt ：
Q14527
Organism ：
Homo sapiens
Expression system ：
E. coli
Tag ：
No tag
Sequence ：
V58-A174
Assay ：
Structure ：
Inquiry ：
是
Symbol/Gene Name: HLTF
Alias: Helicase-like transcription factor,DNA-binding protein/plasminogen activator inhibitor 1 regulator,HIP116,RING finger protein 80,RING-type E3 ubiquitin transferase HLTF,SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3,Sucrose nonfermenting protein 2-like 3
Uniprot: Q14527
Background: Has both helicase and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity; This activity may be required for transcriptional activation or repression of specific target promoters (By similarity). These may include the SERPINE1 and HIV-1 promoters and the SV40 enhancer, to which this protein can bind directly. Plays a role in error-free postreplication repair (PRR) of damaged DNA and maintains genomic stability through acting as a ubiquitin ligase for 'Lys-63'-linked polyubiquitination of chromatin-bound PCNA.
Construct: (GG)-HLTF(V58-A174)
Expression Host: E. coli
Purity: 90%
Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
Supplied as sterile
Please contact us for any concerns or special requirements.
Please refer to the specific buffer information in the hard copy of CoA.
Endotoxin:
< 0.01 EU per μg of the protein
Shipping:
Liquid. It is shipped out with blue ice.
Stability & Storage:
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Recombinant protein