ABCA1-H134A
Family ：
ABC
Catalog No. ：
ABCA1-H134A
Protein ：
ABCA1
UniProt ：
O95477
Organism ：
Homo sapiens
Expression system ：
Insect cell
Tag ：
Flag,Strep II,8His
Sequence ：
A2-V2261
Assay ：
Structure ：
Inquiry ：
是
Symbol/Gene Name: ABCA1 (ABC1, CERP)
Alias: Phospholipid-transporting ATPase ABCA1
Uniprot: O95477
Background: Catalyzes the translocation of specific phospholipids from the cytoplasmic to the extracellular/lumenal leaflet of membrane coupled to the hydrolysis of ATP(PubMed:24097981). Thereby, participates in phospholipid transfer to apoliproteins to form nascent high density lipoproteins/HDLs (PubMed:14754908). Transports preferentially phosphatidylcholine over phosphatidylserine (PubMed:24097981). May play a similar role in the efflux of intracellular cholesterol to apoliproteins and the formation of nascent high density lipoproteins/HDLs (PubMed:10533863, PubMed:14754908, PubMed:24097981).
Construct: 8His-Strep II-TEV-(GG)-ABCA1(A2-V2261 end)-Flag
Expression Host: Insect cell
Purity: 90%
Formulation: 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
Please contact us for any concerns or special requirements.
Please refer to the specific buffer information in the hard copy of CoA.
Endotoxin:
< 0.01 EU per μg of the protein
Shipping:
Liquid. It is shipped out with blue ice.
Stability & Storage:
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Recombinant protein