Family :


Catalog No. :


Protein :


UniProt :


Organism :

Homo sapiens

Expression system :

Mammalian cell

Tag :

eGFP,Strep II,10His

Sequence :


Assay :

Structure :

Inquiry :

Symbol/Gene Name:  ABCB1

Alias:  ATP-dependent translocase ABCB1,ATP-binding cassette sub-family B member 1,Multidrug resistance protein 1,P-glycoprotein 1,Phospholipid transporter ABCB1,CD243

Uniprot: P08183

Background: Translocates drugs and phospholipids across the membrane (PubMed:8898203, PubMed:2897240, PubMed:9038218). Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane. Participates mainly to the flop of phosphatidylcholine, phosphatidylethanolamine, beta-D-glucosylceramides and sphingomyelins (PubMed:8898203). Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells (PubMed:2897240, PubMed:9038218).

Construct: ABCB1(M1-Q1280 end) (E566Q, E1201Q)-3C-eGFP-Strep II-10His

Expression Host: Mammalian


Formulation: 20 mM HEPES pH 7.5, 150 mM NaCl, 0.005% (w/v) GDN, 0.0005% (w/v) CHS

Please contact us for any concerns or special requirements.

Please refer to the specific buffer information in the hard copy of CoA.


< 0.01 EU per μg of the protein


Liquid. It is shipped out with blue ice.

Stability & Storage:

Samples are stable for up to twelve months from date of receipt at -20 to -80

Store it under sterile conditions at -20 to -80. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.