ABCB1-H31E
Family ：
ABC
Catalog No. ：
ABCB1-H31E
Protein ：
ABCB1
UniProt ：
P08183
Organism ：
Homo sapiens
Expression system ：
Mammalian cell
Tag ：
eGFP,Strep II,10His
Sequence ：
M1-Q1280
Assay ：
Structure ：
Inquiry ：
是
Symbol/Gene Name: ABCB1
Alias: ATP-dependent translocase ABCB1,ATP-binding cassette sub-family B member 1,Multidrug resistance protein 1,P-glycoprotein 1,Phospholipid transporter ABCB1,CD243
Uniprot: P08183
Background: Translocates drugs and phospholipids across the membrane (PubMed:8898203, PubMed:2897240, PubMed:9038218). Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane. Participates mainly to the flop of phosphatidylcholine, phosphatidylethanolamine, beta-D-glucosylceramides and sphingomyelins (PubMed:8898203). Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells (PubMed:2897240, PubMed:9038218).
Construct: ABCB1(M1-Q1280 end) (E566Q, E1201Q)-3C-eGFP-Strep II-10His
Expression Host: Mammalian
Purity:
Formulation: 20 mM HEPES pH 7.5, 150 mM NaCl, 0.005% (w/v) GDN, 0.0005% (w/v) CHS
Please contact us for any concerns or special requirements.
Please refer to the specific buffer information in the hard copy of CoA.
Endotoxin:
< 0.01 EU per μg of the protein
Shipping:
Liquid. It is shipped out with blue ice.
Stability & Storage:
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Recombinant protein