表达系统
- 分类：蛋白制备
- 发布时间：2020-08-14 00:00:00
- 访问量：0
概要:In Biortus, we utilise all major expression hosts, E.coli, yeast, insect and mammalian cells for our protein expression purposes. Since establishment, we have successfully delivered over 500 recombinant proteins, mostly enzymes and membrane proteins. The enzymes range from kinases, reductases, polymerases to epigenetic targets and others. One of the membrane proteins that we produced from scratch in four months was later crystallised by our crystallography team, adding a novel membrane protein structure to the company portfolio in a total of just eight months.
Besides conventional recombinant proteins, Biortus has protocol in place for customised protein modification such as Se-Met derivatisation, isotope labelling, biotinylation, PEG modification and more. Upon request, we can also deliver gram scale reagent grade antibodies for our clients in 6-8 weeks.
详情
佰翱得已成熟利用所有主流表达系统来获得目标蛋白，例如：大肠杆菌、酵母、昆虫细胞和哺乳动物细胞表达系统。自从公司建立以来，我们已经成功表达了超过2000种重组蛋白，其中大多数是酶和膜蛋白。酶包括表观遗传学靶标的蛋白激酶、还原酶、聚合酶等等。并且曾经我们成功完成的一个膜蛋白项目。
除了传统的重组蛋白之外，佰翱得还有按客户要求定制蛋白特殊修饰的服务项目，例如硒代修饰、同位素标记、生物素化、PEG修饰等。根据要求，我们还可以在6-8周内为客户提供克级的抗体。
